Overexpression of Telomerase Protects Human and Murine Lung Epithelial Cells from Fas- and Bleomycin-Induced Apoptosis via FLIP Upregulation

High doses of bleomycin administered to patients with lymphomas and other tumors lead to significant lung toxicity in general, and to apoptosis of epithelial cells, in particular. Apoptosis of alveolar epithelium is an important step in the pathogenesis of bleomycin-induced pulmonary fibrosis. The F...

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Detalles Bibliográficos
Autores principales: Arish, Nissim, Cohen, Pazit Y., Golan-Gerstl, Regina, Fridlender, Zvi, Dayan, Mark Richter, Zisman, Philip, Breuer, Raphael, Wallach-Dayan, Shulamit B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423936/
https://www.ncbi.nlm.nih.gov/pubmed/25951185
http://dx.doi.org/10.1371/journal.pone.0126730

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423936/
https://www.ncbi.nlm.nih.gov/pubmed/25951185
http://dx.doi.org/10.1371/journal.pone.0126730

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