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Overexpression of Telomerase Protects Human and Murine Lung Epithelial Cells from Fas- and Bleomycin-Induced Apoptosis via FLIP Upregulation
High doses of bleomycin administered to patients with lymphomas and other tumors lead to significant lung toxicity in general, and to apoptosis of epithelial cells, in particular. Apoptosis of alveolar epithelium is an important step in the pathogenesis of bleomycin-induced pulmonary fibrosis. The F...
Autores principales: | Arish, Nissim, Cohen, Pazit Y., Golan-Gerstl, Regina, Fridlender, Zvi, Dayan, Mark Richter, Zisman, Philip, Breuer, Raphael, Wallach-Dayan, Shulamit B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423936/ https://www.ncbi.nlm.nih.gov/pubmed/25951185 http://dx.doi.org/10.1371/journal.pone.0126730 |
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