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High Affinity Antibodies against Influenza Characterize the Plasmablast Response in SLE Patients After Vaccination
Breakdown of B cell tolerance is a cardinal feature of systemic lupus erythematosus (SLE). Increased numbers of autoreactive mature naïve B cells have been described in SLE patients and autoantibodies have been shown to arise from autoreactive and non-autoreactive precursors. How these defects, in t...
Autores principales: | , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423960/ https://www.ncbi.nlm.nih.gov/pubmed/25951191 http://dx.doi.org/10.1371/journal.pone.0125618 |