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piRNAs from Pig Testis Provide Evidence for a Conserved Role of the Piwi Pathway in Post-Transcriptional Gene Regulation in Mammals

Piwi-interacting (pi-) RNAs guide germline-expressed Piwi proteins in order to suppress the activity of transposable elements (TEs). But notably, the majority of pachytene piRNAs in mammalian testes is not related to TEs. This raises the question of whether the Piwi/piRNA pathway exerts functions be...

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Detalles Bibliográficos
Autores principales: Gebert, Daniel, Ketting, René F., Zischler, Hans, Rosenkranz, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423968/
https://www.ncbi.nlm.nih.gov/pubmed/25950437
http://dx.doi.org/10.1371/journal.pone.0124860