An Exclusion Zone for Ca(2+) Channels around Docked Vesicles Explains Release Control by Multiple Channels at a CNS Synapse

The spatial arrangement of Ca(2+) channels and vesicles remains unknown for most CNS synapses, despite of the crucial importance of this geometrical parameter for the Ca(2+) control of transmitter release. At a large model synapse, the calyx of Held, transmitter release is controlled by several Ca(2...

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Detalles Bibliográficos
Autores principales: Keller, Daniel, Babai, Norbert, Kochubey, Olexiy, Han, Yunyun, Markram, Henry, Schürmann, Felix, Schneggenburger, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423980/
https://www.ncbi.nlm.nih.gov/pubmed/25951120
http://dx.doi.org/10.1371/journal.pcbi.1004253

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423980/
https://www.ncbi.nlm.nih.gov/pubmed/25951120
http://dx.doi.org/10.1371/journal.pcbi.1004253

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