Innate immune restriction and antagonism of viral RNA lacking 2׳-O methylation

N-7 and 2′-O methylation of host cell mRNA occurs in the nucleus and results in the generation of cap structures (cap 0, m(7)GpppN; cap 1, m(7)GpppNm) that control gene expression by modulating nuclear export, splicing, turnover, and protein synthesis. Remarkably, RNA cap modification also contribut...

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Detalles Bibliográficos
Autores principales: Hyde, Jennifer L., Diamond, Michael S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4424151/
https://www.ncbi.nlm.nih.gov/pubmed/25682435
http://dx.doi.org/10.1016/j.virol.2015.01.019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4424151/
https://www.ncbi.nlm.nih.gov/pubmed/25682435
http://dx.doi.org/10.1016/j.virol.2015.01.019

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