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Innate immune restriction and antagonism of viral RNA lacking 2׳-O methylation
N-7 and 2′-O methylation of host cell mRNA occurs in the nucleus and results in the generation of cap structures (cap 0, m(7)GpppN; cap 1, m(7)GpppNm) that control gene expression by modulating nuclear export, splicing, turnover, and protein synthesis. Remarkably, RNA cap modification also contribut...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier Inc.
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4424151/ https://www.ncbi.nlm.nih.gov/pubmed/25682435 http://dx.doi.org/10.1016/j.virol.2015.01.019 |