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Lapatinib access into normal brain and brain metastases in patients with Her-2 overexpressing breast cancer

BACKGROUND: Brain metastases are common in human epidermal growth factor receptor (Her)-2-positive breast cancer. Drug access to brain metastases and normal brain is key to management of cranial disease. In this study, positron emission tomography (PET) scanning after administration of radiolabelled...

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Detalles Bibliográficos
Autores principales: Saleem, Azeem, Searle, Graham E, Kenny, Laura M, Huiban, Mickael, Kozlowski, Kasia, Waldman, Adam D, Woodley, Laura, Palmieri, Carlo, Lowdell, Charles, Kaneko, Tomomi, Murphy, Philip S, Lau, Mike R, Aboagye, Eric O, Coombes, Raoul C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4424224/
https://www.ncbi.nlm.nih.gov/pubmed/25977884
http://dx.doi.org/10.1186/s13550-015-0103-5