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The Effect of Cadmium on COX-1 and COX-2 Gene, Protein Expression, and Enzymatic Activity in THP-1 Macrophages

The aim of this study was to examine the effects of cadmium in concentrations relevant to those detected in human serum on cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) expression at mRNA, protein, and enzyme activity levels in THP-1 macrophages. Macrophages were incubated with various cadmi...

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Detalles Bibliográficos
Autores principales: Olszowski, Tomasz, Gutowska, Izabela, Baranowska-Bosiacka, Irena, Piotrowska, Katarzyna, Korbecki, Jan, Kurzawski, Mateusz, Chlubek, Dariusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4424267/
https://www.ncbi.nlm.nih.gov/pubmed/25645360
http://dx.doi.org/10.1007/s12011-015-0234-6