A Randomized, Placebo-Controlled Trial of Lubiprostone for Opioid-Induced Constipation in Chronic Noncancer Pain

OBJECTIVES: This multicenter, phase 3 trial evaluated oral lubiprostone for constipation associated with non-methadone opioids in patients with chronic noncancer-related pain. METHODS: Adults with opioid-induced constipation (OIC; <3 spontaneous bowel movements [SBMs] per week) were randomized 1:...

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Detalles Bibliográficos
Autores principales: Jamal, M Mazen, Adams, Atoya B, Jansen, Jan-Peter, Webster, Lynn R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Functional GI Disorders
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4424379/
https://www.ncbi.nlm.nih.gov/pubmed/25916220
http://dx.doi.org/10.1038/ajg.2015.106

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4424379/
https://www.ncbi.nlm.nih.gov/pubmed/25916220
http://dx.doi.org/10.1038/ajg.2015.106

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