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A major population of mucosal memory CD4(+) T cells, coexpressing IL-18Rα and DR3, display innate lymphocyte functionality

Mucosal tissues contain large numbers of memory CD4(+) T cells that, through T-cell receptor-dependent interactions with antigen-presenting cells, are believed to have a key role in barrier defense and maintenance of tissue integrity. Here we identify a major subset of memory CD4(+) T cells at barri...

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Detalles Bibliográficos
Autores principales: Holmkvist, P, Roepstorff, K, Uronen-Hansson, H, Sandén, C, Gudjonsson, S, Patschan, O, Grip, O, Marsal, J, Schmidtchen, A, Hornum, L, Erjefält, J S, Håkansson, K, Agace, W W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4424383/
https://www.ncbi.nlm.nih.gov/pubmed/25269704
http://dx.doi.org/10.1038/mi.2014.87