Cargando…

Histone Deacetylase Inhibitors (HDACi) Cause the Selective Depletion of Bromodomain Containing Proteins (BCPs)

Histone deacetylases (HDACs) and acetyltransferases control the epigenetic regulation of gene expression through modification of histone marks. Histone deacetylase inhibitors (HDACi) are small molecules that interfere with histone tail modification, thus altering chromatin structure and epigenetical...

Descripción completa

Detalles Bibliográficos
Autores principales: Mackmull, Marie-Therese, Iskar, Murat, Parca, Luca, Singer, Stephan, Bork, Peer, Ori, Alessandro, Beck, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4424404/
https://www.ncbi.nlm.nih.gov/pubmed/25755299
http://dx.doi.org/10.1074/mcp.M114.042499