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Division of labor between IRF1 and IRF2 in regulating different stages of transcriptional activation in cellular antiviral activities
BACKGROUND: Cellular antiviral activities are critically controlled by transcriptional activation of interferon-inducible genes, involving interferon regulatory factors (IRFs). Previous data suggested that IRF1 is an activator and IRF2 is a repressor, which functionally antagonize each other in tran...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4424430/ https://www.ncbi.nlm.nih.gov/pubmed/25960866 http://dx.doi.org/10.1186/s13578-015-0007-0 |