Division of labor between IRF1 and IRF2 in regulating different stages of transcriptional activation in cellular antiviral activities

BACKGROUND: Cellular antiviral activities are critically controlled by transcriptional activation of interferon-inducible genes, involving interferon regulatory factors (IRFs). Previous data suggested that IRF1 is an activator and IRF2 is a repressor, which functionally antagonize each other in tran...

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Detalles Bibliográficos
Autores principales: Ren, Gang, Cui, Kairong, Zhang, Zhiying, Zhao, Keji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4424430/
https://www.ncbi.nlm.nih.gov/pubmed/25960866
http://dx.doi.org/10.1186/s13578-015-0007-0

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