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Utilization of a genetically modified muscle flap for local BMP-2 production and its effects on bone healing: a histomorphometric and radiological study in a rat model

AIM OF THE STUDY: We developed an experimental rat model to explore the possibility of enhancing the healing of critical-size bone defects. The aim of this study was to demonstrate the feasibility of this concept by achieving high local BMP-2 expression via a transduced muscle flap that would facili...

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Detalles Bibliográficos
Autores principales: Lampert, Florian M, Momeni, Arash, Filev, Filip, Torio-Padron, Nestor, Finkenzeller, Günter, Stark, G Björn, Steiner, Dominik, Koulaxouzidis, Georgios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4424495/
https://www.ncbi.nlm.nih.gov/pubmed/25924919
http://dx.doi.org/10.1186/s13018-015-0196-6