Statin-induced anti-proliferative effects via cyclin D1 and p27 in a window-of-opportunity breast cancer trial

PURPOSE: Cholesterol lowering statins have been demonstrated to exert anti-tumoral effects on breast cancer by decreasing proliferation as measured by Ki67. The biological mechanisms behind the anti-proliferative effects remain elusive. The aim of this study was to investigate potential statin-induc...

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Detalles Bibliográficos
Autores principales: Feldt, Maria, Bjarnadottir, Olöf, Kimbung, Siker, Jirström, Karin, Bendahl, Pär-Ola, Veerla, Srinivas, Grabau, Dorthe, Hedenfalk, Ingrid, Borgquist, Signe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4424530/
https://www.ncbi.nlm.nih.gov/pubmed/25925673
http://dx.doi.org/10.1186/s12967-015-0486-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4424530/
https://www.ncbi.nlm.nih.gov/pubmed/25925673
http://dx.doi.org/10.1186/s12967-015-0486-0

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