The HBx oncoprotein of hepatitis B virus potentiates cell transformation by inducing c-Myc-dependent expression of the RNA polymerase I transcription factor UBF

BACKGROUND: The HBx oncoprotein of hepatitis B virus has been implicated in the development and progression of hepatocellular carcinoma (HCC). HBx engages multiple signalling and growth-promoting pathways to induce cell proliferation and enhance ribosome biogenesis. Interestingly, the levels of Upst...

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Detalles Bibliográficos
Autores principales: Rajput, Pallavi, Shukla, Surendra Kumar, Kumar, Vijay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4424551/
https://www.ncbi.nlm.nih.gov/pubmed/25890091
http://dx.doi.org/10.1186/s12985-015-0293-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4424551/
https://www.ncbi.nlm.nih.gov/pubmed/25890091
http://dx.doi.org/10.1186/s12985-015-0293-5

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