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The HBx oncoprotein of hepatitis B virus potentiates cell transformation by inducing c-Myc-dependent expression of the RNA polymerase I transcription factor UBF

BACKGROUND: The HBx oncoprotein of hepatitis B virus has been implicated in the development and progression of hepatocellular carcinoma (HCC). HBx engages multiple signalling and growth-promoting pathways to induce cell proliferation and enhance ribosome biogenesis. Interestingly, the levels of Upst...

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Detalles Bibliográficos
Autores principales:	Rajput, Pallavi, Shukla, Surendra Kumar, Kumar, Vijay
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4424551/ https://www.ncbi.nlm.nih.gov/pubmed/25890091 http://dx.doi.org/10.1186/s12985-015-0293-5

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