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A novel vaccine for mantle cell lymphoma based on targeting cyclin D1 to dendritic cells via CD40

BACKGROUND: Mantle cell lymphoma (MCL) is a distinct clinical pathologic subtype of B cell non-Hodgkin’s lymphoma often associated with poor prognosis. New therapeutic approaches based on boosting anti-tumor immunity are needed. MCL is associated with overexpression of cyclin D1 thus rendering this...

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Detalles Bibliográficos
Autores principales: Chen, Jingtao, Zurawski, Gerard, Zurawski, Sandy, Wang, Zhiqing, Akagawa, Keiko, Oh, Sangkon, Hideki, Ueno, Fay, Joseph, Banchereau, Jacques, Song, Wenru, Palucka, A Karolina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4424584/
https://www.ncbi.nlm.nih.gov/pubmed/25888530
http://dx.doi.org/10.1186/s13045-015-0131-7