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A novel vaccine for mantle cell lymphoma based on targeting cyclin D1 to dendritic cells via CD40
BACKGROUND: Mantle cell lymphoma (MCL) is a distinct clinical pathologic subtype of B cell non-Hodgkin’s lymphoma often associated with poor prognosis. New therapeutic approaches based on boosting anti-tumor immunity are needed. MCL is associated with overexpression of cyclin D1 thus rendering this...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4424584/ https://www.ncbi.nlm.nih.gov/pubmed/25888530 http://dx.doi.org/10.1186/s13045-015-0131-7 |