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IL-6, through p-STAT3 rather than p-STAT1, activates hepatocarcinogenesis and affects survival of hepatocellular carcinoma patients: a cohort study

BACKGROUND: Biologic activities of functional mediators activate downstream transducers regulating inflammation and carcinogenesis. Correlation among mediators (IL-6, IL-27, TNF-α, and VEGF) with STAT proteins at diverse clinical-pathologic stages of hepatocellular carcinoma (HCC) remains limited. M...

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Detalles Bibliográficos
Autores principales: Kao, Jung-Ta, Feng, Chun-Lung, Yu, Cheng-Ju, Tsai, Shu-Mei, Hsu, Ping-Ning, Chen, Yao-Li, Wu, Yi-Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4424593/
https://www.ncbi.nlm.nih.gov/pubmed/25908103
http://dx.doi.org/10.1186/s12876-015-0283-5