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Expression of Glutamine Transporter Slc38a3 (SNAT3) During Acidosis is Mediated by a Different Mechanism than Tissue-Specific Expression

BACKGROUND: Despite homeostatic pH regulation, systemic and cellular pH changes take place and strongly influence metabolic processes. Transcription of the glutamine transporter SNAT3 (Slc38a3) for instance is highly up-regulated in the kidney during metabolic acidosis to provide glutamine for ammon...

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Detalles Bibliográficos
Autores principales: Balkrishna, Sarojini, Bröer, Angelika, Welford, Scott M., Hatzoglou, Maria, Bröer, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4424794/
https://www.ncbi.nlm.nih.gov/pubmed/24854847
http://dx.doi.org/10.1159/000358722