Cargando…

Hemopexin in severe inflammation and infection: mouse models and human diseases

INTRODUCTION: Cell-free plasma hemoglobin is associated with poor outcome in patients with sepsis. Extracellular hemoglobin and secondarily released heme amplify inflammation in the presence of microbial TLR ligands and/or endogenous mediators. Hemopexin, a plasma protein that binds heme with extrao...

Descripción completa

Detalles Bibliográficos
Autores principales: Lin, Tian, Maita, Dayana, Thundivalappil, Sujatha R, Riley, Frank E, Hambsch, Jasmin, Van Marter, Linda J, Christou, Helen A, Berra, Lorenzo, Fagan, Shawn, Christiani, David C, Warren, H Shaw
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4424824/
https://www.ncbi.nlm.nih.gov/pubmed/25888135
http://dx.doi.org/10.1186/s13054-015-0885-x