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Hemopexin in severe inflammation and infection: mouse models and human diseases
INTRODUCTION: Cell-free plasma hemoglobin is associated with poor outcome in patients with sepsis. Extracellular hemoglobin and secondarily released heme amplify inflammation in the presence of microbial TLR ligands and/or endogenous mediators. Hemopexin, a plasma protein that binds heme with extrao...
Autores principales: | Lin, Tian, Maita, Dayana, Thundivalappil, Sujatha R, Riley, Frank E, Hambsch, Jasmin, Van Marter, Linda J, Christou, Helen A, Berra, Lorenzo, Fagan, Shawn, Christiani, David C, Warren, H Shaw |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4424824/ https://www.ncbi.nlm.nih.gov/pubmed/25888135 http://dx.doi.org/10.1186/s13054-015-0885-x |
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