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Intracellular calcium dynamics in cortical microglia responding to focal laser injury in the PC::G5-tdT reporter mouse

Microglia, the resident immune cells of the brain parenchyma, are highly responsive to tissue injury. Following cell damage, microglial processes redirect their motility from randomly scouting the extracellular space to specifically reaching toward the compromised tissue. While the cell morphology a...

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Detalles Bibliográficos
Autores principales: Pozner, Amir, Xu, Ben, Palumbos, Sierra, Gee, J. Michael, Tvrdik, Petr, Capecchi, Mario R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4424843/
https://www.ncbi.nlm.nih.gov/pubmed/26005403
http://dx.doi.org/10.3389/fnmol.2015.00012