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Differential expression of sirtuins in the aging rat brain

Although there are seven mammalian sirtuins (SIRT1-7), little is known about their expression in the aging brain. To characterize the change(s) in mRNA and protein expression of SIRT1-7 and their associated proteins in the brain of “physiologically” aged Wistar rats. We tested mRNA and protein expre...

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Detalles Bibliográficos
Autores principales: Braidy, Nady, Poljak, Anne, Grant, Ross, Jayasena, Tharusha, Mansour, Hussein, Chan-Ling, Tailoi, Smythe, George, Sachdev, Perminder, Guillemin, Gilles J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4424846/
https://www.ncbi.nlm.nih.gov/pubmed/26005404
http://dx.doi.org/10.3389/fncel.2015.00167