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Identification of pneumococcal colonization determinants in the stringent response pathway facilitated by genomic diversity
BACKGROUND: Understanding genetic determinants of a microbial phenotype generally involves creating and comparing isogenic strains differing at the locus of interest, but the naturally existing genomic and phenotypic diversity of microbial populations has rarely been exploited. Here we report use of...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4424882/ https://www.ncbi.nlm.nih.gov/pubmed/25956132 http://dx.doi.org/10.1186/s12864-015-1573-6 |