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Identification of pneumococcal colonization determinants in the stringent response pathway facilitated by genomic diversity

BACKGROUND: Understanding genetic determinants of a microbial phenotype generally involves creating and comparing isogenic strains differing at the locus of interest, but the naturally existing genomic and phenotypic diversity of microbial populations has rarely been exploited. Here we report use of...

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Detalles Bibliográficos
Autores principales: Li, Yuan, Croucher, Nicholas J, Thompson, Claudette M, Trzciński, Krzysztof, Hanage, William P, Lipsitch, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4424882/
https://www.ncbi.nlm.nih.gov/pubmed/25956132
http://dx.doi.org/10.1186/s12864-015-1573-6