Transcriptional implications of intragenic DNA methylation in the oestrogen receptor alpha gene in breast cancer cells and tissues

BACKGROUND: DNA methylation variability regions (MVRs) across the oestrogen receptor alpha (ESR1) gene have been identified in peripheral blood cells from breast cancer patients and healthy individuals. In contrast to promoter methylation, gene body methylation may be important in maintaining active...

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Detalles Bibliográficos
Autores principales: Shenker, Natalie S, Flower, Kirsty J, Wilhelm-Benartzi, Charlotte S, Dai, Wei, Bell, Emma, Gore, Edmund, El Bahrawy, Mona, Weaver, Gillian, Brown, Robert, Flanagan, James M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4424887/
https://www.ncbi.nlm.nih.gov/pubmed/25927974
http://dx.doi.org/10.1186/s12885-015-1335-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4424887/
https://www.ncbi.nlm.nih.gov/pubmed/25927974
http://dx.doi.org/10.1186/s12885-015-1335-5

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