Loss of the scavenger mRNA decapping enzyme DCPS causes syndromic intellectual disability with neuromuscular defects

mRNA decay is an essential and active process that allows cells to continuously adapt gene expression to internal and environmental cues. There are two mRNA degradation pathways: 3′ to 5′ and 5′ to 3′. The DCPS protein is the scavenger mRNA decapping enzyme which functions in the last step of the 3′...

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Detalles Bibliográficos
Autores principales: Ng, Calista K.L., Shboul, Mohammad, Taverniti, Valerio, Bonnard, Carine, Lee, Hane, Eskin, Ascia, Nelson, Stanley F., Al-Raqad, Mohammed, Altawalbeh, Samah, Séraphin, Bertrand, Reversade, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4424953/
https://www.ncbi.nlm.nih.gov/pubmed/25712129
http://dx.doi.org/10.1093/hmg/ddv067

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4424953/
https://www.ncbi.nlm.nih.gov/pubmed/25712129
http://dx.doi.org/10.1093/hmg/ddv067

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