Impairing Eukaryotic Elongation Factor 2 Kinase Activity Decreases Atherosclerotic Plaque Formation

We tested whether loss of eukaryotic elongation factor 2 kinase (eEF2K) activity in macrophages suppresses development of atherosclerosis by transplanting bone marrow from mice with mutant eEF2K into ldlr(−/−) mice. Sixteen weeks after high-fat diet feeding, mutant eEF2K hematopoietic chimeras had a...

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Detalles Bibliográficos
Autores principales: Zhang, Peng, Riazy, Maziar, Gold, Matthew, Tsai, Shu-Huei, McNagny, Kelly, Proud, Christopher, Duronio, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pulsus Group 2014
Materias:
Brief Rapid Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4424975/
https://www.ncbi.nlm.nih.gov/pubmed/25475470
http://dx.doi.org/10.1016/j.cjca.2014.09.019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4424975/
https://www.ncbi.nlm.nih.gov/pubmed/25475470
http://dx.doi.org/10.1016/j.cjca.2014.09.019

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