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Limitations and Extensions of the Lock-and-Key Principle: Differences between Gas State, Solution and Solid State Structures
The lock-and-key concept is discussed with respect to necessary extensions. Formation of supramolecular complexes depends not only, and often not even primarily on an optimal geometric fit between host and guest. Induced fit and allosteric interactions have long been known as important modifications...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4424984/ https://www.ncbi.nlm.nih.gov/pubmed/25815592 http://dx.doi.org/10.3390/ijms16046694 |