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Glycolic Acid-Catalyzed Deamidation of Asparagine Residues in Degrading PLGA Matrices: A Computational Study

Poly(lactic-co-glycolic acid) (PLGA) is a strong candidate for being a drug carrier in drug delivery systems because of its biocompatibility and biodegradability. However, in degrading PLGA matrices, the encapsulated peptide and protein drugs can undergo various degradation reactions, including deam...

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Detalles Bibliográficos
Autores principales:	Manabe, Noriyoshi, Kirikoshi, Ryota, Takahashi, Ohgi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425015/ https://www.ncbi.nlm.nih.gov/pubmed/25837471 http://dx.doi.org/10.3390/ijms16047261

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