Biological Mechanisms Underlying the Ultraviolet Radiation-Induced Formation of Skin Wrinkling and Sagging II: Over-Expression of Neprilysin Plays an Essential Role

Our previous studies strongly indicated that the up-regulated activity of skin fibroblast-derived elastase plays a pivotal role in wrinkling and/or sagging of the skin via the impairment of elastic fiber configuration and the subsequent loss of skin elasticity. Fortunately, we succeeded in identifyi...

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Detalles Bibliográficos
Autores principales: Imokawa, Genji, Nakajima, Hiroaki, Ishida, Koichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425049/
https://www.ncbi.nlm.nih.gov/pubmed/25856676
http://dx.doi.org/10.3390/ijms16047776

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425049/
https://www.ncbi.nlm.nih.gov/pubmed/25856676
http://dx.doi.org/10.3390/ijms16047776

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