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RNA Sequencing Identifies Upregulated Kyphoscoliosis Peptidase and Phosphatidic Acid Signaling Pathways in Muscle Hypertrophy Generated by Transgenic Expression of Myostatin Propeptide

Myostatin (MSTN), a member of the transforming growth factor-β superfamily, plays a crucial negative role in muscle growth. MSTN mutations or inhibitions can dramatically increase muscle mass in most mammal species. Previously, we generated a transgenic mouse model of muscle hypertrophy via the tran...

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Detalles Bibliográficos
Autores principales: Miao, Yuanxin, Yang, Jinzeng, Xu, Zhong, Jing, Lu, Zhao, Shuhong, Li, Xinyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425062/
https://www.ncbi.nlm.nih.gov/pubmed/25860951
http://dx.doi.org/10.3390/ijms16047976