Addition of Interleukin-21 for Expansion of T-Cells for Adoptive Immunotherapy of Murine Melanoma

We previously demonstrated that interleukin (IL)-7/15 was superior to IL-2 for expansion of T cells in vitro for adoptive immunotherapy. We sought to ascertain whether IL-21 would further improve yield and therapeutic efficacy of T cells in culture. Naïve T cell receptor (TcR) transgenic splenocytes...

Descripción completa

Detalles Bibliográficos
Autores principales: Zoon, Christine Kathryn, Wan, Wen, Graham, Laura, Bear, Harry D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425106/
https://www.ncbi.nlm.nih.gov/pubmed/25903148
http://dx.doi.org/10.3390/ijms16048744

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425106/
https://www.ncbi.nlm.nih.gov/pubmed/25903148
http://dx.doi.org/10.3390/ijms16048744

Ejemplares similares