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Structural dynamics and inhibitor searching for Wnt-4 protein using comparative computational studies
Wnt-4 (wingless mouse mammary tumor virus integration site-4) protein is involved in many crucial embryonic pathways regulating essential processes. Aberrant Wnt-4 activity causes various anomalies leading to gastric, colon, or breast cancer. Wnt-4 is a conserved protein in structure and sequence. A...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425240/ https://www.ncbi.nlm.nih.gov/pubmed/25995617 http://dx.doi.org/10.2147/DDDT.S79784 |