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Fine Mapping of a GWAS-Derived Obesity Candidate Region on Chromosome 16p11.2
INTRODUCTION: Large-scale genome-wide association studies (GWASs) have identified 97 chromosomal loci associated with increased body mass index in population-based studies on adults. One of these SNPs, rs7359397, tags a large region (approx. 1MB) with high linkage disequilibrium (r²>0.7), which c...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425372/ https://www.ncbi.nlm.nih.gov/pubmed/25955518 http://dx.doi.org/10.1371/journal.pone.0125660 |