Cargando…
Fine Mapping of a GWAS-Derived Obesity Candidate Region on Chromosome 16p11.2
INTRODUCTION: Large-scale genome-wide association studies (GWASs) have identified 97 chromosomal loci associated with increased body mass index in population-based studies on adults. One of these SNPs, rs7359397, tags a large region (approx. 1MB) with high linkage disequilibrium (r²>0.7), which c...
Autores principales: | Volckmar, Anna-Lena, Song, Jie-Yun, Jarick, Ivonne, Pütter, Carolin, Göbel, Maria, Horn, Lucie, Struve, Christoph, Haas, Katharina, Knoll, Nadja, Grallert, Harald, Illig, Thomas, Reinehr, Thomas, Wang, Hai-Jun, Hebebrand, Johannes, Hinney, Anke |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425372/ https://www.ncbi.nlm.nih.gov/pubmed/25955518 http://dx.doi.org/10.1371/journal.pone.0125660 |
Ejemplares similares
-
Mutation screen in the GWAS derived obesity gene SH2B1 including functional analyses of detected variants
por: Volckmar, Anna-Lena, et al.
Publicado: (2012) -
Analysis of Genes Involved in Body Weight Regulation by Targeted Re-Sequencing
por: Volckmar, Anna-Lena, et al.
Publicado: (2016) -
Gene Set of Nuclear-Encoded Mitochondrial Regulators Is Enriched for Common Inherited Variation in Obesity
por: Knoll, Nadja, et al.
Publicado: (2013) -
Mitochondrial DNA Variants in Obesity
por: Knoll, Nadja, et al.
Publicado: (2014) -
Investigation of a Genome Wide Association Signal for Obesity: Synthetic Association and Haplotype Analyses at the Melanocortin 4 Receptor Gene Locus
por: Scherag, André, et al.
Publicado: (2010)