Combining GWAS and RNA-Seq Approaches for Detection of the Causal Mutation for Hereditary Junctional Epidermolysis Bullosa in Sheep

In this study, we demonstrate the use of a genome-wide association mapping together with RNA-seq in a reduced number of samples, as an efficient approach to detect the causal mutation for a Mendelian disease. Junctional epidermolysis bullosa is a recessive genodermatosis that manifests with neonatal...

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Detalles Bibliográficos
Autores principales: Suárez-Vega, Aroa, Gutiérrez-Gil, Beatriz, Benavides, Julio, Perez, Valentín, Tosser-Klopp, Gwenola, Klopp, Christophe, Keennel, Stephen J., Arranz, Juan José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425408/
https://www.ncbi.nlm.nih.gov/pubmed/25955497
http://dx.doi.org/10.1371/journal.pone.0126416

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425408/
https://www.ncbi.nlm.nih.gov/pubmed/25955497
http://dx.doi.org/10.1371/journal.pone.0126416

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