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Identification and Analysis of the Paulomycin Biosynthetic Gene Cluster and Titer Improvement of the Paulomycins in Streptomyces paulus NRRL 8115

The paulomycins are a group of glycosylated compounds featuring a unique paulic acid moiety. To locate their biosynthetic gene clusters, the genomes of two paulomycin producers, Streptomyces paulus NRRL 8115 and Streptomyces sp. YN86, were sequenced. The paulomycin biosynthetic gene clusters were de...

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Detalles Bibliográficos
Autores principales: Li, Jine, Xie, Zhoujie, Wang, Min, Ai, Guomin, Chen, Yihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425429/
https://www.ncbi.nlm.nih.gov/pubmed/25822496
http://dx.doi.org/10.1371/journal.pone.0120542