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Coadministration of the Three Antigenic Leishmania infantum Poly (A) Binding Proteins as a DNA Vaccine Induces Protection against Leishmania major Infection in BALB/c Mice

BACKGROUND: Highly conserved intracellular proteins from Leishmania have been described as antigens in natural and experimental infected mammals. The present study aimed to evaluate the antigenicity and prophylactic properties of the Leishmania infantum Poly (A) binding proteins (LiPABPs). METHODOLO...

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Detalles Bibliográficos
Autores principales: Soto, Manuel, Corvo, Laura, Garde, Esther, Ramírez, Laura, Iniesta, Virginia, Bonay, Pedro, Gómez-Nieto, Carlos, González, Víctor M., Martín, M. Elena, Alonso, Carlos, Coelho, Eduardo A. F., Barral, Aldina, Barral-Netto, Manoel, Iborra, Salvador
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425485/
https://www.ncbi.nlm.nih.gov/pubmed/25955652
http://dx.doi.org/10.1371/journal.pntd.0003751