PKM2 Subcellular Localization Is Involved in Oxaliplatin Resistance Acquisition in HT29 Human Colorectal Cancer Cell Lines

Chemoresistance is the main cause of treatment failure in advanced colorectal cancer (CRC). However, molecular mechanisms underlying this phenomenon remain to be elucidated. In a previous work we identified low levels of PKM2 as a putative oxaliplatin-resistance marker in HT29 CRC cell lines and als...

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Detalles Bibliográficos
Autores principales: Ginés, Alba, Bystrup, Sara, Ruiz de Porras, Vicenç, Guardia, Cristina, Musulén, Eva, Martínez-Cardús, Anna, Manzano, José Luis, Layos, Laura, Abad, Albert, Martínez-Balibrea, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425499/
https://www.ncbi.nlm.nih.gov/pubmed/25955657
http://dx.doi.org/10.1371/journal.pone.0123830

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425499/
https://www.ncbi.nlm.nih.gov/pubmed/25955657
http://dx.doi.org/10.1371/journal.pone.0123830

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