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Resveratrol Ameliorates Renal Damage, Increases Expression of Heme Oxygenase-1, and Has Anti-Complement, Anti-Oxidative, and Anti-Apoptotic Effects in a Murine Model of Membranous Nephropathy

BACKGROUND: Idiopathic membranous nephropathy (MN) is an autoimmune-mediated glomerulonephritis and a common cause of nephrotic syndrome in adults. There are limited available treatments for MN. We assessed the efficacy of resveratrol (RSV) therapy for treatment of MN in a murine model of this disea...

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Detalles Bibliográficos
Autores principales: Wu, Chia-Chao, Huang, Yen-Sung, Chen, Jin-Shuen, Huang, Ching-Feng, Su, Sui-Lung, Lu, Kuo-Cheng, Lin, Yuh-Feng, Chu, Pauling, Lin, Shih-Hua, Sytwu, Huey-Kang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425525/
https://www.ncbi.nlm.nih.gov/pubmed/25954969
http://dx.doi.org/10.1371/journal.pone.0125726