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Ionic Selectivity and Permeation Properties of Human PIEZO1 Channels

Members of the eukaryotic PIEZO family (the human orthologs are noted hPIEZO1 and hPIEZO2) form cation-selective mechanically-gated channels. We characterized the selectivity of human PIEZO1 (hPIEZO1) for alkali ions: K(+), Na(+), Cs(+) and Li(+); organic cations: TMA and TEA, and divalents: Ba(2+),...

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Detalles Bibliográficos
Autores principales: Gnanasambandam, Radhakrishnan, Bae, Chilman, Gottlieb, Philip A., Sachs, Frederick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425559/
https://www.ncbi.nlm.nih.gov/pubmed/25955826
http://dx.doi.org/10.1371/journal.pone.0125503