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Ionic Selectivity and Permeation Properties of Human PIEZO1 Channels
Members of the eukaryotic PIEZO family (the human orthologs are noted hPIEZO1 and hPIEZO2) form cation-selective mechanically-gated channels. We characterized the selectivity of human PIEZO1 (hPIEZO1) for alkali ions: K(+), Na(+), Cs(+) and Li(+); organic cations: TMA and TEA, and divalents: Ba(2+),...
Autores principales: | Gnanasambandam, Radhakrishnan, Bae, Chilman, Gottlieb, Philip A., Sachs, Frederick |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425559/ https://www.ncbi.nlm.nih.gov/pubmed/25955826 http://dx.doi.org/10.1371/journal.pone.0125503 |
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