Natural Killer Cell Sensing of Infected Cells Compensates for MyD88 Deficiency but Not IFN-I Activity in Resistance to Mouse Cytomegalovirus

In mice, plasmacytoid dendritic cells (pDC) and natural killer (NK) cells both contribute to resistance to systemic infections with herpes viruses including mouse Cytomegalovirus (MCMV). pDCs are the major source of type I IFN (IFN-I) during MCMV infection. This response requires pDC-intrinsic MyD88...

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Detalles Bibliográficos
Autores principales: Cocita, Clément, Guiton, Rachel, Bessou, Gilles, Chasson, Lionel, Boyron, Marilyn, Crozat, Karine, Dalod, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425567/
https://www.ncbi.nlm.nih.gov/pubmed/25954804
http://dx.doi.org/10.1371/journal.ppat.1004897

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425567/
https://www.ncbi.nlm.nih.gov/pubmed/25954804
http://dx.doi.org/10.1371/journal.ppat.1004897

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