Human Cytomegalovirus miR-UL112-3p Targets TLR2 and Modulates the TLR2/IRAK1/NFκB Signaling Pathway

Human Cytomegalovirus (HCMV) encodes multiple microRNAs (miRNAs) whose functions are just beginning to be uncovered. Using in silico approaches, we identified the Toll-Like Receptor (TLR) innate immunity pathway as a possible target of HCMV miRNAs. Luciferase reporter assay screens further identifie...

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Detalles Bibliográficos
Autores principales: Landais, Igor, Pelton, Chantel, Streblow, Daniel, DeFilippis, Victor, McWeeney, Shannon, Nelson, Jay A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425655/
https://www.ncbi.nlm.nih.gov/pubmed/25955717
http://dx.doi.org/10.1371/journal.ppat.1004881

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425655/
https://www.ncbi.nlm.nih.gov/pubmed/25955717
http://dx.doi.org/10.1371/journal.ppat.1004881

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