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Structural Conversion of Aβ(17–42) Peptides from Disordered Oligomers to U-Shape Protofilaments via Multiple Kinetic Pathways
Discovering the mechanisms by which proteins aggregate into fibrils is an essential first step in understanding the molecular level processes underlying neurodegenerative diseases such as Alzheimer’s and Parkinson's. The goal of this work is to provide insights into the structural changes that...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425657/ https://www.ncbi.nlm.nih.gov/pubmed/25955249 http://dx.doi.org/10.1371/journal.pcbi.1004258 |