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Recovery of Cognitive Dysfunction via Orally Administered Redox-Polymer Nanotherapeutics in SAMP8 Mice

Excessively generated reactive oxygen species are associated with age-related neurodegenerative diseases. We investigated whether scavenging of reactive oxygen species in the brain by orally administered redox nanoparticles, prepared by self-assembly of redox polymers possessing antioxidant nitroxid...

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Detalles Bibliográficos
Autores principales: Chonpathompikunlert, Pennapa, Yoshitomi, Toru, Vong, Long Binh, Imaizumi, Natsuka, Ozaki, Yuki, Nagasaki, Yukio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425673/
https://www.ncbi.nlm.nih.gov/pubmed/25955022
http://dx.doi.org/10.1371/journal.pone.0126013