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Recovery of Cognitive Dysfunction via Orally Administered Redox-Polymer Nanotherapeutics in SAMP8 Mice
Excessively generated reactive oxygen species are associated with age-related neurodegenerative diseases. We investigated whether scavenging of reactive oxygen species in the brain by orally administered redox nanoparticles, prepared by self-assembly of redox polymers possessing antioxidant nitroxid...
Autores principales: | Chonpathompikunlert, Pennapa, Yoshitomi, Toru, Vong, Long Binh, Imaizumi, Natsuka, Ozaki, Yuki, Nagasaki, Yukio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425673/ https://www.ncbi.nlm.nih.gov/pubmed/25955022 http://dx.doi.org/10.1371/journal.pone.0126013 |
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