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Maximal Expression of Foxl2 in Pituitary Gonadotropes Requires Ovarian Hormones
Gonadotropin-releasing hormone (GnRH) and activin regulate synthesis of FSH and ultimately fertility. Recent in vivo studies cast SMAD4 and FOXL2 as master transcriptional mediators of activin signaling that act together and independently of GnRH to regulate Fshb gene expression and female fertility...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425675/ https://www.ncbi.nlm.nih.gov/pubmed/25955311 http://dx.doi.org/10.1371/journal.pone.0126527 |